Available in Brazil
It will test, in a proof-of-concept study, the antidepressant efficacy of adjunctive
administration of probiotics in bipolar depression and evaluate potential inflammatory and
metabolic markers associated with response to treatment. With this objective, 84 individuals
with bipolar disorder type I or type II presenting subsyndromal depressive symptoms or a
major depressive episode will be recruited. The study design lasts 12 weeks and is expected
to last two years.
1Research sites
84Patients around the world
