Last updated 52 days ago
Rose Bengal Electromagnetic Activation With Green Light for Infection Reduction II
60 patients around the world
Available in Brazil
University of California, San Francisco
1Research sites
60Patients around the world
This study is for people with
Bacterial Keratitis
Requirements for the patient
From 18 Years
All Gender
Medical requirements
- Corneal ulcer that is smear positive and/or culture positive (within 24 hours) for typical bacteria (i.e. non-Nocardia or Myobacteria).Moderate to severe vision loss, defined as Snellen visual acuity of 20/40 (6/12) or worse.Corneal thickness ≥350 µm, as measured on AS-OCT.Age over 18 years.Basic understanding of the study as determined by the physician.Commitment to return for follow up visits.
- Evidence of concomitant infection on exam, gram stain, or confocal microscopy (i.e. herpes, both bacteria and acanthamoeba on gram stain).Impending or frank perforation at recruitment.Involvement of sclera at presentation.Presence of desmetocele at recruitment.Non-infectious or autoimmune keratitis.History of corneal transplantation.History of intraocular surgery within the last three months.Pinhole visual acuity worse than 20/200 in the unaffected eye.Participants who are decisionally and/or cognitively impaired.
Sites
Universidad Federal de São Paulo - Unifesp
StudyREAGIR II
SponsorUniversity of California, San Francisco
Conditions
Requirements
From 18 YearsAll Gender
Unique study IDclinicaltrials.gov
NCT06271772
