Last updated 5 days ago

Parasitic Ulcer Treatment Trial

232 patients around the world

Available in Brazil, United States

Jeremy Keenan, MD, MPH

1Research sites

232Patients around the world

Requirements for the patient

From 8 Years

All Gender

: AK on at least one of the following: culture, smear, PCR, shotgun sequencing, biopsy, or confocal microscopy
Ocular inflammation after 1 month of anti-amoebic treatment, defined as conjunctival, corneal, episcleral, or anterior chamber inflammation

: Evidence or history of interstitial keratitis
Known herpetic keratitis, as determined from history, exam, or microbiological testing
Known fungal keratitis, as demonstrated from corneal scrapings
Corneal perforation or impending corneal perforation
Prior therapeutic keratoplasty for acanthamoeba keratitis
Unwillingness or inability to follow-up
No light perception in the affected eye
Known hypertensive response to steroids
Corticosteroid allergy
Concurrent treatment with systemic corticosteroids
Concurrent granulomatous amoebic encephalitis

Universidad Federal de São Paulo - Unifesp

R. Sena Madureira, 1500 - Vila Clementino, São Paulo - SP, 04021-001

StudyPUTT

SponsorJeremy Keenan, MD, MPH

Requirements

From 8 YearsAll Gender

Unique study IDclinicaltrials.gov

NCT06213649