Last updated 7 months ago
Effects of Paroxetine on Cardiovascular Function in Septic Patients
92 patients around the world
Available in Brazil
Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude
2Research sites
92Patients around the world
Requirements for the patient
From 18 Years
All Gender
Medical requirements
- Patient over 18 years of age;Patient diagnosed with septic shock for less than 48 hours and using a minimum dose of noradrenaline (0.01 mcg/kg/min);Patients and/or legal guardians who consented to participate in the study through the free and informed consent term before randomization.
- Pregnant women;Patients with inability to use the gastrointestinal tract;Patients with known intolerance to paroxetine and/or fluoxetine;Patients on concomitant use of medications that may potentiate the occurrence of serotonin syndrome (tramadol, citalopram, escitalopram, sertraline, desvenlafaxine, venlafaxine, duloxetine, sibutramine, bupropion, amitriptyline, nortriptyline, lithium);Patients in end-of-life care or with an expected survival of less than 24 hours at the time of eligibility
Sites
Hospital Maternidade São José
Recruiting
Centro de Pesquisa Hospital São José - Centro Criciúma/SC
Recruiting
SponsorUniversidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude
Requirements
From 18 YearsAll Gender
Unique study IDclinicaltrials.gov
NCT05725837
