Available in Argentina, United States
This is an extension study for participants aged 6 to 17 with migraine who completed
either studies 19356A (NCT04965675) (chronic migraine [CM] study in adolescents) or
19357A (episodic migraine [EM] study in children and adolescents). All participants who
complete the Week 12 visit of the respective lead-in study will be offered participation
in this open-label extension (OLE) study, unless there is a safety concern precluding a
participant's participation in the study. Participants originally randomized to 100
milligrams (mg) (weight adjusted) in the double-blind lead-in study (Study 19356A or
Study 19357A) will continue on the same dose (100 mg, weight adjusted) in the OLE study.
Participants randomized to the 300 mg dose (weight adjusted) in the double-blind lead-in
study will continue on 300 mg (weight adjusted) in the OLE study. Participants who were
assigned to placebo in the double-blind lead-in study will be randomly allocated to one
of the two treatment groups: eptinezumab 100 mg (weight adjusted) or eptinezumab 300 mg
(weight adjusted) with a ratio of 1:1.
7Research sites
600Patients around the world