Last updated 3 years ago

Percutaneous Revascularization in Infarction With Late Presentation and Absence of Viability: Effects on Left Ventricular Remodeling and Contractility

70 patients around the world

Available in Brazil

The purpose of this study is to evaluate whether late recanalization in patients with ST elevation myocardial infarction (STEMI) without Viability on Cardiovascular Magnetic Resonance can reduce the reverse remodeling through the reduction of the End Systolic Volume (ESV) at 6 months and through the improvement in segmental contractility of infarcted related artery at MRI.

Instituto Dante Pazzanese de Cardiologia

70Patients around the world

Requirements for the patient

To 80 Years

All Gender

Medical requirements

: STEMI not reperfused between 24 hours and 28 days
MI-related artery with > or = 50%
Segmental dysfunction in the artery related to infarction.
Technical feasibility for PCI recanalization
Absence of Myocardial Viability

: Age > 80 years
< 1 year life expectancy
Post MI Angina
Clinical Instability
Electrical Instability
Previous Infarction with segment disfunction
New York Heart Association (NYHA) class III or IV of heart failure.
Previous diagnosis of congestive heart failure or cardiomyopathy
Severe heart valve disease
Absence of segmental dysfunction in the artery related to infarction
Coronary angiography without obstructive lesions
Indication of myocardial revascularization surgery
Opted for clinical treatment for technical reasons
Serum creatinine concentration greater than 2.5 mg/dl
Pacemaker or Implantable Cardiodefibrillator (ICD)
Brain Clip Carriers
Patients with Cochlear Implants
Refusal to sign the Informed Consent Form (ICF).
Inability to maintain outpatient follow-up for 6 months.

SponsorInstituto Dante Pazzanese de Cardiologia

Study typeInterventional

Requirements

To 80 YearsAll Gender

Unique study IDclinicaltrials.gov

NCT05160311