Ultrasound Imaging Based Sensing of Human Ankle Motion Intent and Control Strategies for Ankle Assistance
25 patients around the world
Robotic therapies aim to improve limb function in individuals with neurological injury. Modulation of robotic assistance in many of these therapies is achieved by measuring the extant volitional strength of limb muscles. However, current sensing techniques, such as electromyography, are often unable to correctly measure the voluntary strength of a targeted muscle. The difficulty is due to their inability to remove ambiguity caused by interference from activities of neighboring muscles. These discrepancies in the measurement can cause the robot to provide inadequate assistance or over-assistance. Improper robotic assistance slows function recovery, and can potentially lead to falls during robot-assisted walking. An ultrasound imaging approach is an alternative voluntary strength detection methodology, which can allow direct visualization and measurement of muscle contraction activities. The aim is to formulate an electromyography-ultrasound imaging-based technique to sense residual voluntary strength in ankle muscles for individuals with neuromuscular disorders. The estimated voluntary strength will be involved in the advanced controller's design of robotic rehabilitative devices, including powered ankle exoskeleton and functional electrical stimulation system.
It is hypothesized that the ankle joint voluntary strength will be estimated more accurately by using the proposed electromyography-ultrasound imaging-based technique. And this will help the robotic rehabilitative devices achieve a more adaptive and efficient assistance control, and maximize the ankle joint rehabilitation training benefits.
Available in United States
North Carolina State University
2Research sites
25Patients around the world
This study is for people with
Acute transverse myelitis
Requirements for the patient
To 64 years
All Gender
Medical requirements
for participants without neurological disorders: Age between the ages of 18 and 64
for participants without neurological disorders: Weight less than 220 lb
for participants without neurological disorders: Able to perform ankle movements such as ankle up motion, ankle down motion, side motion towards inside, and side motion towards outside while seated
for participants without neurological disorders: Able to walk normally at a preferred speed without any assistive device
for participants with neurological disorders: 18-64 years of age and have a primary diagnosis of traumatic/non-traumatic iSCI or demyelinating diseases like transverse myelitis
for participants with neurological disorders: Weight less than 220 lb
for participants with neurological disorders: Sub-acute or chronic phase (at least 3 months after injury) incomplete motor lesion (AIS C or D at enrollment) at cervical, thoracic or lumbar level
for participants with neurological disorders: Ability to ambulate over ground independent using either a cane or rolling walker, as well as those that do not require any assistive devices but do have some mobility difficulties
for participants with neurological disorders: Medically stable with medical clearance for participation, no evidence of cardiopulmonary or pulmonary disease, severe spasticity, and asymmetric hip positions
for participants with neurological disorders: Ability to respond to FES on dorsiflexors and plantarflexors
for participants with neurological disorders: No use of any FES devices or already in use of a FES device for mobility support (like a Bioness device) but will not use the device during the study
for participants without neurological disorders: Any difficulty or an orthopedic condition that would impede ankle movements such as ankle up motion, ankle down motion, side motion towards inside, and side motion towards outside
for participants without neurological disorders: Any difficulty walking normally or without assistance
for participants without neurological disorders: Absence of sensation in lower extremities
for participants without neurological disorders: An allergy to adhesive skin tapes and/or US gels
for participants without neurological disorders: Pregnant Females
for participants without neurological disorders: No ankle muscle response to FES
for participants with neurological disorders: Subjects with other neuromuscular diseases such as polio, stroke, or multiple sclerosis
for participants with neurological disorders: Presence of transmissible diseases such as (but not limited to) hepatitis or immunodeficiency virus
for participants with neurological disorders: Any clinical condition contraindicating gait
for participants with neurological disorders: Untreatable chronic pain
for participants with neurological disorders: Severe spasticity (Ashworth scale score > 3)
for participants with neurological disorders: Severe reduction in lower limb joint Range of Motion (ROM) higher than 20 deg
for participants with neurological disorders: At a high risk of a fracture from osteoporosis
for participants with neurological disorders: Any skin problem inhibiting robot usage, major depression or psychosis
for participants with neurological disorders: Subjects with heart conditions and pacemakers
for participants with neurological disorders: Concurrent severe medical disease, pressure sores, open wounds, existing infection, unstable spine, unhealed limber pelvic fractures, history of recurrent fractures, known orthopedic injury to lower extremities, and osteoporosis
for participants with neurological disorders: Have open wounds
for participants with neurological disorders: Pregnant Females
for participants with neurological disorders: No ankle muscle response to FES
Sites
UNC Center for Rehabilitation Care
Recruiting
1807 Fordham Blvd, Chapel Hill, NC 27514
NC State University Centennial Campus - Engineering Building III (EB3)