Effect of Simvastatin on Sepsis and Febrile Neutropenia in Patients With Acute Lymphoblastic Leukemia
108 patients around the world
Available in Mexico
Death associated with sepsis is one of the principal complications related to chemotherapy
treatment; there are currently no strategies to prevent its development besides the use of
prophylactic antibiotics or granulocyte colony stimulants to reduce the period of febrile
neutropenia. Most of the trials on the use of statins are retrospective with controversial
results and include patients with different clinical situations that conditioned the septic
study.