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A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis

1185 patients around the world

Available in Puerto Rico, Spain, Colombia, United States, Mexico, Chile, Peru, Argentina, Brazil

Bristol-Myers Squibb

29Research sites

1185Patients around the world

This study is for people with

Pulmonary fibrosis

Idiopathic pulmonary fibrosis

Requirements for the patient

From 40 Years

All Gender

Medical requirements

: Subjects with IPF aged ≥ 40 years at the time of signing the informed consent.
Diagnosis of IPF within 7 years prior to screening that is supported by centrally read chest high-resolution computed tomography (HRCT) obtained at screening and verification of usual interstitial pneumonia.
If on pirfenidone or nintedanib, participants must have been on a stable dose for at least 90 days prior to screening.
If not currently on pirfenidone or nintedanib, participants must not have received either of these medications within 28 days prior to screening.
Women who are of childbearing potential must have a highly effective form of contraception and must provide a negative urine/serum pregnancy test.
Men who are sexually active with women of childbearing potential agree to use male barrier contraception.

: History of stroke or transient ischemic attack within 3 months prior to screening.
Participants who exhibit symptoms of heart failure at rest.
Participants who have a current malignancy or a previous malignancy in the past 5 years prior to screening, except for those who have a documented history of cured nonmetastatic squamous cell skin carcinoma, basal cell skin carcinoma, or cervical carcinoma in situ.
Other protocol-defined Inclusion/Exclusion criteria apply.

Sites

Centro de Investigación del Maule - Talca

Recruiting

Calle 30 Ote. 1562, of 701, 3460000 Talca, Maule, Chile

CEC Centros Estudios Clínicos

Recruiting

Av. Irarrázaval 2401, 7750495 Ñuñoa, Región Metropolitana, Chile

Hospital Clínico Regional de Concepción Dr. Guillermo Grant Benavente - Concepción, Chile

Recruiting

San Martín 1436, Concepción, Bío Bío

Centro de Investigación Curicó

Recruiting

Manuel Montt 378, Oficina 32, 3341643 Curicó, Maule, Chile

CENRESIN - Centro Respiratorio Integral

Recruiting

San Martín 502, 2261076 Quillota, Valparaíso, Chile

Clínica Universidad de los Andes

Recruiting

Av Plaza 2501, Las Condes, Región Metropolitana, Santiago

Instituto Nacional del Tórax - Santiago de Chile

Recruiting

José Manuel Infante 717, Providencia, Región Metropolitana, Chile

The Lung Research Center

Recruiting

222 S Woods Mill Rd #300n, Chesterfield, MO 63017, USA

Meris Clinical Research

Recruiting

310 Oakfield Dr c, Brandon, FL 33511, USA

Christiana Care Pulmonary Associates - Newark

Recruiting

4735 Ogletown Stanton Rd, Newark, DE 19713, USA

SponsorBristol-Myers Squibb

Conditions

Idiopathic pulmonary fibrosis

Requirements

From 40 YearsAll Gender

Unique study IDclinicaltrials.gov

NCT06003426