Last updated 8 days ago
A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis
1185 patients around the world
Available in Puerto Rico, Spain, Colombia, United States, Mexico, Chile, Peru, Argentina, Brazil
Bristol-Myers Squibb
64Research sites
1185Patients around the world
This study is for people with
Pulmonary fibrosis
Idiopathic pulmonary fibrosis
Requirements for the patient
From 40 Years
All Gender
Medical requirements
- Subjects with IPF aged ≥ 40 years at the time of signing the informed consent.Diagnosis of IPF within 7 years prior to screening that is supported by centrally read chest high-resolution computed tomography (HRCT) obtained at screening and verification of usual interstitial pneumonia.If on pirfenidone or nintedanib, participants must have been on a stable dose for at least 90 days prior to screening.If not currently on pirfenidone or nintedanib, participants must not have received either of these medications within 28 days prior to screening.Women who are of childbearing potential must have a highly effective form of contraception and must provide a negative urine/serum pregnancy test.Men who are sexually active with women of childbearing potential agree to use male barrier contraception.
- History of stroke or transient ischemic attack within 3 months prior to screening.Participants who exhibit symptoms of heart failure at rest.Participants who have a current malignancy or a previous malignancy in the past 5 years prior to screening, except for those who have a documented history of cured nonmetastatic squamous cell skin carcinoma, basal cell skin carcinoma, or cervical carcinoma in situ.Other protocol-defined Inclusion/Exclusion criteria apply.
Sites
Centro Respiratorio Quilmes - Buenos Aires
Recruiting
Instituto Médico de la Fundación Estudios Clínicos - Rosario
Recruiting
Instituto del Buen Aire
Recruiting
Instituto Médico Damic S.R.L.
Recruiting
Centro de Investigaciones Metabólicas (CINME) S.A. - CABA, Buenos Aires
Recruiting
Instituto de Investigaciones en Patologías Respiratorias SRL - Tucumán
Recruiting
Respira Salud Clínica Integral
Recruiting
Fundación Enfisema - Instituto Ave Pulmo
Recruiting
Fundación Respirar
Recruiting
Consultorios Médicos del Buen Ayre
Recruiting
SponsorBristol-Myers Squibb
Study typeInterventional
Conditions
Idiopathic pulmonary fibrosis
Requirements
From 40 YearsAll Gender
Unique study IDclinicaltrials.gov
NCT06003426
