Last updated 30 days ago
A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC)
1000 patients around the world
Available in Costa Rica, Chile, United States, Brazil, Argentina, Mexico
Hoffmann-La Roche
9Research sites
1000Patients around the world
This study is for people with
Lung cancer
Non-small cell lung carcinoma
Requirements for the patient
From 18 Years
All Gender
Medical requirements
- Histologically or cytologically confirmed diagnosis of unresectable Stage IIIb not amenable to treatment with combined modality chemoradiation (advanced) or Stage IV (metastatic) NSCLCEastern Cooperative Oncology Group (ECOG) Performance Status 0-2Measurable diseaseAdequate recovery from most recent systemic or local treatment for cancerAdequate organ functionLife expectancy greater than or equal to (>/=) 12 weeksFor female participants of childbearing potential and male participants, willingness to use acceptable methods of contraception
- Inability to swallow oral medicationWomen who are pregnant or lactatingSymptomatic, untreated CNS metastasesHistory of malignancy other than NSCLC within 5 years prior to screening with the exception of malignancies with negligible risk of metastasis or deathSignificant cardiovascular disease, such as New York Heart Association cardiac disease (Class II or greater), myocardial infarction, or cerebrovascular accident within 3 months prior to randomization, unstable arrhythmias, or unstable anginaKnown human immunodeficiency virus (HIV) positivity or autoimmune deficiency syndrome (AIDS)-related illnessEither a concurrent condition or history of a prior condition that places the patient at unacceptable risk if he/she were treated with the study drug or confounds the ability to interpret data from the studyInability to comply with other requirements of the protocol
Sites
Fundación Cori para la Investigación y Prevención del Cáncer - La Rioja
Recruiting
Hospital Británico de Buenos Aires - CABA
Recruiting
Hospital Italiano de Buenos Aires - CABA, Buenos Aires
Fundación CENIT para la Investigación en Neurociencias
Recruiting
Centro de Investigación Clínica Bradford Hill - Santiago, Región Metropolitana
Recruiting
Oncológico Potosino
Recruiting
Avix Investigación Clínica S.C
Recruiting
Hospital Ángeles Tijuana
Recruiting
Health Pharma Professional Research
Recruiting
StudyB-FAST
SponsorHoffmann-La Roche
Study typeInterventional
Conditions
Non-small cell lung carcinomaLung cancer
Requirements
From 18 YearsAll Gender
Unique study IDclinicaltrials.gov
NCT03178552
